Functional Attributes in Pathways

• Substrates : 478 entries in CutDB for S01.010 Ext
  • A kinase (PRKA) anchor protein 8-like
  • 100 kDa hexon-assembly associated protein
  • 2',3'-cyclic nucleotide 3' phosphodiesterase
  • 3'-terminal phosphate cyclase
  • 40S ribosomal protein S11
  • 40S ribosomal protein S15
  • 40S ribosomal protein S15a
  • 40S ribosomal protein S21
  • 40S ribosomal protein S3a
  • 40S ribosomal protein S4
  • 40S ribosomal protein S7
  • 40S ribosomal protein S8
  • 6-phosphofructokinase, liver type
  • 6-phosphofructokinase, muscle type
  • 60S ribosomal protein L10
  • 60S ribosomal protein L11
  • 60S ribosomal protein L13
  • 60S ribosomal protein L28
  • 60S ribosomal protein L4
  • A kinase anchor protein 8
  • A-kinase anchor protein 8
  • acetyl-Coenzyme A carboxylase alpha
  • acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
  • acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
  • Acidic leucine-rich nuclear phosphoprotein 32 family member A
  • Acidic leucine-rich nuclear phosphoprotein 32 family member B
  • actin, beta
  • Actin, cytoplasmic 1
  • actin, gamma 2 propeptide
  • Actin, gamma-enteric smooth muscle
  • Actin-like protein 6A
  • activating transcription factor 7 interacting protein
  • ADP-ribosylation factor-like 6 interacting protein 4
  • alanyl-tRNA synthetase
  • Alpha-enolase
  • ankyrin 1 isoform 1
  • ankyrin repeat and KH domain containing 1 isoform 1
  • ankyrin repeat and KH domain containing 1 isoform 2
  • ankyrin repeat and KH domain containing 1 isoform 3
  • ankyrin repeat domain protein 17 isoform a
  • ankyrin repeat domain protein 17 isoform b
  • antigen identified by monoclonal antibody Ki-67 isoform 1
  • antigen identified by monoclonal antibody Ki-67 isoform 2
  • ataxin 3 isoform 1
  • ataxin 3 isoform 2
  • ataxin 3 isoform 3
  • ataxin 3 isoform 4
  • ATP synthase subunit alpha, mitochondrial precursor
  • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit precursor
  • ATP-binding cassette sub-family F member 2
  • ATP-binding cassette, sub-family F (GCN20), member 1
  • ATP-binding cassette, sub-family F (GCN20), member 2
  • BCL2-associated athanogene isoform 1L
  • BCL2-associated transcription factor 1 isoform 1
  • BCL2/adenovirus E1B 19kD interacting protein 2
  • BH3 interacting domain death agonist isoform 1
  • Bh3 interacting domain death agonist isoform 2
  • biorientation of chromosomes in cell division 1-like
  • BMS1-like, ribosome assembly protein
  • calcium/calmodulin-dependent protein kinase IV
  • caspase 10 isoform a preproprotein
  • caspase 10 isoform b preproprotein
  • Caspase 10 isoform d preproprotein
  • Caspase 3 preproprotein
  • caspase 7 isoform alpha precursor
  • Caspase 7 isoform delta
  • caspase 8 isoform A precursor
  • caspase 8 isoform B precursor
  • caspase 8 isoform C precursor
  • caspase 8 isoform G precursor
  • Caspase 9 isoform alpha preproprotein
  • Cell death regulator Aven
  • Cell division cycle 5-like protein
  • cell division cycle associated 5
  • centromere protein B
  • chaperonin
  • chromodomain helicase DNA binding protein 4
  • chromodomain helicase DNA binding protein 7
  • Chromodomain-helicase-DNA-binding protein 4
  • Clathrin light chain B
  • cleavage and polyadenylation specific factor 6
  • CLIP-associating protein 1 isoform 1
  • coiled-coil domain containing 104
  • conserved nuclear protein Nhn1 isoform a
  • conserved nuclear protein Nhn1 isoform b
  • cyclin-dependent kinase inhibitor 1A
  • cytokine induced apoptosis inhibitor 1
  • D4, zinc and double PHD fingers family 2
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3
  • DEAH (Asp-Glu-Ala-His) box polypeptide 38
  • DEAH (Asp-Glu-Ala-His) box polypeptide 8
  • death inducer-obliterator 1 isoform 2
  • death inducer-obliterator 1 isoform 3
  • dedicator of cyto-kinesis 2
  • delangin isoform A
  • delangin isoform B
  • dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
  • DNA fragmentation factor subunit alpha
  • Dna fragmentation factor, 45kda, alpha polypeptide isoform 1
  • DNA fragmentation factor, 45kDa, alpha polypeptide isoform 2
  • DNA mismatch repair protein Msh6
  • DNA polymerase delta catalytic subunit
  • DNA replication licensing factor MCM2
  • DNA replication licensing factor MCM3
  • DNA replication licensing factor MCM5
  • DNA topoisomerase 1
  • DNA topoisomerase I
  • DNA-dependent protein kinase catalytic subunit
  • DNA-directed DNA polymerase delta 4
  • DNA-directed RNA polymerase I A
  • DNA-directed RNA polymerase I subunit RPA1
  • DnaJ homolog subfamily C member 7
  • DnaJ homolog, subfamily C, member 9
  • Double-strand break repair protein MRE11A
  • Dynactin subunit 2
  • E3 ubiquitin-protein ligase HUWE1
  • Elongation factor 1-alpha 1
  • elongation factor Tu GTP binding domain containing 2 isoform a
  • elongation factor Tu GTP binding domain containing 2 isoform b
  • Endoplasmin
  • enhancer of mRNA decapping 3
  • enolase 1, alpha non-neuron
  • ErbB3-binding protein 1
  • eukaryotic translation initiation factor 2 subunit 2
  • eukaryotic translation initiation factor 3, subunit 1 alpha, 35kDa
  • eukaryotic translation initiation factor 3, subunit 10 (theta)
  • eukaryotic translation initiation factor 3, subunit J
  • Eukaryotic translation initiation factor 4 gamma 1
  • eukaryotic translation initiation factor 4, gamma 2 isoform 1
  • eukaryotic translation initiation factor 4, gamma 2 isoform 2
  • eukaryotic translation initiation factor 4H
  • Eukaryotic translation initiation factor 5A-1
  • Exportin-5
  • fibrillarin
  • fibronectin 1 isoform 1 preproprotein
  • filamin A, alpha
  • FK506 binding protein 5
  • Flt3 interacting zinc finger protein 1
  • fragile X mental retardation-related protein 2
  • FtsJ homolog 3
  • G protein-coupled receptor kinase interacting ArfGAP 2 isoform 1
  • G protein-coupled receptor kinase interacting ArfGAP 2 isoform 2
  • G protein-coupled receptor kinase interacting ArfGAP 2 isoform 3
  • gamma-taxilin
  • general transcription factor II E, polypeptide 1 (alpha subunit)
  • general transcription factor III C 1
  • Glutamate receptor 3 isoform flop precursor
  • glutamate-rich 1
  • GTP binding protein 1
  • GTP binding protein 4
  • H2A histone family, member Z
  • HBS1-like protein
  • heat shock 70kD protein binding protein
  • heat shock 90kDa protein 1, alpha isoform 1
  • heat shock 90kDa protein 1, beta
  • heat shock protein beta-1
  • helicase (DNA) B
  • hematopoietic cell specific Lyn substrate 1
  • hepatoma-derived growth factor-related protein 2
  • Heterogeneous nuclear ribonucleoprotein A3
  • heterogeneous nuclear ribonucleoprotein C
  • heterogeneous nuclear ribonucleoprotein F
  • heterogeneous nuclear ribonucleoprotein K
  • Heterogeneous nuclear ribonucleoprotein K
  • heterogeneous nuclear ribonucleoprotein M isoform a
  • heterogeneous nuclear ribonucleoprotein M isoform b
  • heterogeneous nuclear ribonucleoprotein U
  • hexamethylene bis-acetamide inducible 1
  • high mobility group nucleosomal binding domain 1
  • histidyl-tRNA synthetase
  • histone deacetylase 2
  • hnRNP-associated with lethal yellow long isoform
  • hnRNP-associated with lethal yellow short isoform
  • IK cytokine
  • Isoleucyl-tRNA synthetase, cytoplasmic
  • IST1 homolog
  • IWS1 homolog
  • janus kinase and microtubule interacting protein 1
  • karyopherin alpha 4
  • KH-type splicing regulatory protein
  • kinesin family member 4
  • la related protein
  • Lamin b1
  • laminin alpha 5
  • lens epithelium-derived growth factor
  • leucine rich repeat (in FLII) interacting protein 1 isoform 1
  • leupaxin
  • LTV1 homolog
  • LUC7-like 2
  • Lupus La protein (Sjoegren syndrome type B antigen)
  • Ly1 antibody reactive clone
  • M phase phosphoprotein 6
  • matrin 3
  • microtubule-associated protein 4
  • midasin
  • minichromosome maintenance deficient 3
  • mitogen-activated protein kinase kinase 6
  • Mki67 (FHA domain) interacting nucleolar phosphoprotein
  • mutS homolog 6
  • MYB binding protein (P160) 1a
  • Myb-binding protein 1A
  • myeloid cell leukemia sequence 1 isoform 1
  • myosin XVIIIA
  • NMD3 homolog
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
  • nuclear mitotic apparatus protein 1
  • nuclease sensitive element binding protein 1
  • Nuclease-sensitive element-binding protein 1
  • nucleolar complex associated 2 homolog
  • nucleolar protein 5A
  • nucleolar TGF-beta1 target protein
  • Nucleolin
  • nucleolin
  • Nucleolin (Protein C23)
  • nucleophosmin 1 isoform 1
  • nucleophosmin 1 isoform 2
  • nucleophosmin 1 isoform 3
  • nucleoside-triphosphatase C1orf57
  • Numa protein
  • opioid growth factor receptor
  • otubain 1
  • p66 alpha isoform a
  • p66 alpha isoform b
  • pallidin
  • papillary renal cell carcinoma translocation-associated gene product
  • partner of NOB1
  • PDGFA associated protein 1
  • PDZ and LIM domain 2
  • pericentriolar material 1
  • peter pan homolog
  • PHD finger protein 3
  • phosphofructokinase, liver, B-type
  • phosphofructokinase, platelet
  • pinin
  • Poly (adp-ribose) polymerase family, member 1
  • polyglutamine binding protein 1
  • Polyglutamine-binding protein 1
  • polypyrimidine tract binding protein 1 isoform 1
  • polypyrimidine tract binding protein 1 isoform 2
  • Polypyrimidine tract-binding protein 1
  • postmeiotic segregation 1 isoform a
  • postmeiotic segregation 1 isoform b
  • postmeiotic segregation 1 isoform c
  • postmeiotic segregation increased 2 isoform a
  • procaspase 3
  • procaspase 7
  • proteasome 26S ATPase subunit 2
  • proteasome 26S ATPase subunit 4 isoform 1
  • proteasome 26S ATPase subunit 4 isoform 2
  • proteasome 26S non-ATPase subunit 12
  • protein FAM111A
  • protein kinase C substrate 80K-H
  • Protein kinase, dna-activated, catalytic polypeptide
  • protein LOC66523
  • protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
  • Prothymosin alpha
  • prothymosin alpha
  • PRP3 pre-mRNA processing factor 3 homolog
  • PRP38 pre-mRNA processing factor 38 (yeast) domain containing A
  • PTK2 protein tyrosine kinase 2 isoform a
  • RAN binding protein 2
  • RD RNA-binding protein
  • restin
  • RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
  • Rho GTPase activating protein 15 isoform 1
  • Rho GTPase activating protein 15 isoform 2
  • Rho guanine nucleotide exchange factor (GEF) 1 isoform b
  • Rho guanine nucleotide exchange factor (GEF) 1 isoform c
  • Rho-associated, coiled-coil containing protein kinase 2
  • ribosomal L1 domain containing 1
  • ribosomal protein L17
  • ribosomal protein L18
  • ribosomal protein L23
  • ribosomal protein L24-like
  • ribosomal protein L26-like 1
  • ribosomal protein L3
  • ribosomal protein L35
  • ribosomal protein L4
  • ribosomal protein L5
  • ribosomal protein L6
  • ribosomal protein P0
  • ribosomal protein S13
  • ribosomal protein S15
  • ribosomal protein S27
  • ribosomal protein S4, X-linked
  • ribosomal protein S7
  • ribosomal RNA processing 12 homolog
  • ribosomal RNA processing 8, methyltransferase, homolog
  • RNA binding motif protein 10
  • RNA binding motif protein 34
  • RNA binding motif protein 5
  • RNA binding motif protein 8a isoform a
  • RNA binding motif protein 8a isoform b
  • RNA polymerase II subunit 5-mediating protein
  • RNA polymerase II transcriptional coactivator
  • RNA U, small nuclear RNA export adapter protein
  • ROD1 regulator of differentiation 1
  • RRP15-like protein
  • RRS1 ribosome biogenesis regulator homolog
  • serine/arginine repetitive matrix 2
  • serine/threonine kinase 2
  • serine/threonine kinase 3
  • Serine/threonine-protein kinase N1
  • SERPINE1 mRNA binding protein 1 isoform 1
  • SERPINE1 mRNA binding protein 1 isoform 2
  • SERPINE1 mRNA binding protein 1 isoform 3
  • SERPINE1 mRNA binding protein 1 isoform 4
  • SET binding factor 1
  • SET domain containing 2
  • signal-induced proliferation associated gene 1
  • SKI interacting protein
  • splicing factor 3b, subunit 1
  • splicing factor 3b, subunit 2
  • Splicing factor U2AF 65 kDa subunit
  • splicing factor, arginine/serine-rich 8
  • squamous cell carcinoma antigen recognized by T-cells 3
  • Striatin
  • suppressor of S. cerevisiae gcr2
  • suppressor of Ty 6 homolog
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4
  • T-cell receptor zeta chain isoform 1 precursor
  • T-cell receptor zeta chain isoform 2 precursor
  • taxilin
  • tetratricopeptide repeat domain 39B
  • tetratricopeptide repeat domain 4
  • transcription elongation factor A (SII) 1 isoform 1
  • transcription elongation factor A (SII) 1 isoform 2
  • transcription elongation factor A (SII) 1 isoform 3
  • treacle
  • Tubulin alpha-1A chain
  • tubulin folding cofactor A
  • Tubulin gamma-1 chain
  • tubulin, alpha 1a
  • U1 small nuclear ribonucleoprotein 70 kDa
  • U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
  • U3 snoRNP-associated protein
  • ubiquitin carboxyl-terminal hydrolase L5 isoform 1
  • ubiquitin carboxyl-terminal hydrolase L5 isoform 2
  • Ubiquitin conjugation factor E4 B
  • ubiquitin interaction motif containing 1
  • ubiquitin-conjugating enzyme E2O
  • Ubiquitination factor e4a
  • Uncharacterized protein KIAA0515
  • UTP18, small subunit processome component
  • UV excision repair protein RAD23 homolog A
  • vimentin
  • vitronectin precursor
  • Vpr-binding protein
  • Vps20-associated 1 homolog (S. cerevisiae)
  • WD repeat domain 55
  • Werner helicase interacting protein isoform 1
  • Werner helicase interacting protein isoform 2
  • WNK lysine deficient protein kinase 1
  • Wolf-Hirschhorn syndrome candidate 1
  • X-ray repair cross complementing protein 4 isoform 1
  • Yip1 domain family, member 4
  • zinc finger CCCH-type containing 4
  • Zinc finger CCHC domain-containing protein 8
  • zinc finger protein 191
  • zinc finger protein 295 isoform 1
  • zinc finger protein 295 isoform 2
  • zinc finger protein 295 isoform 3
  • zinedin isoform 1
  • zinedin isoform 2
  • ZW10 interacting protein-1
• Substrate Specificity -- Under development
• Inhibitors -- Under development
• Pathways -- Under development