MMP13
Functional Attributes in Pathways
-
Substrates : 144 entries in CutDB for M10.013
Ext
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aggrecan 1 isoform 1 precursor
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aggrecan 1 isoform 2 precursor
-
Aggrecan 1 isoform 2 precursor
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alpha 1 type I collagen preproprotein
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alpha 1 type II collagen isoform 1
-
alpha 1 type II collagen isoform 2, preproprotein
-
alpha 1 type XVIII collagen isoform 1 precursor
-
alpha 2 type I collagen
-
alpha 2 type IV collagen preproprotein
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biglycan preproprotein
-
Brevican core protein precursor
-
chemokine (C-C motif) ligand 7 precursor
-
chemokine (C-X-C motif) ligand 5
-
Coagulation factor XII precursor
-
coagulation factor XII precursor
-
COL9A1 collagen, type IX, alpha 1
-
collagen alpha 1(I) (Homo sapiens)
-
collagen type III alpha 1 preproprotein
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collagen, type II, alpha 1 isoform 1 precursor
-
collagen, type II, alpha 1 isoform 2 precursor
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connective tissue growth factor
-
decorin isoform a preproprotein
-
decorin isoform b precursor
-
decorin isoform c precursor
-
fibrillin 1
-
fibrinogen, alpha chain isoform alpha preproprotein
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fibrinogen, beta chain preproprotein
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fibrinogen, gamma chain isoform gamma-A precursor
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fibrinogen, gamma chain isoform gamma-B precursor
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Fibromodulin
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fibromodulin precursor
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fibronectin 1
-
growth differentiation factor 5 preproprotein
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heparan sulfate proteoglycan core protein
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interleukin 8 precursor
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laminin, gamma 2
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lumican precursor
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matrix metallopeptidase-13 preproprotein
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matrix metalloproteinase 13 preproprotein
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matrix metalloproteinase 9 preproprotein
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matrix metalloproteinase-13
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Monocyte chemoattractant protein (mcp-3)
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opticin precursor
-
procollagen, type I, alpha 1
-
procollagen, type III, alpha 1
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progelatinase B (Homo sapiens)
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prolactin
-
proline arginine-rich end leucine-rich repeat protein precursor
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secreted protein, acidic, cysteine-rich (osteonectin)
-
serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
-
serpin peptidase inhibitor, clade A, member 3 precursor
-
tenascin C (hexabrachion)
-
transforming growth factor, beta 3
-
Substrate Specificity -- Under development
-
Inhibitors -- Under development
-
Pathways -- Under development
Recent News and Literature
- Bone morphogenetic protein-2 enhances...Bone. 2008 Nov 6.
- [Relationship between the expression...Zhonghua Bing Li Xue Za Zhi. 2008 Jul;37(7):471-6.
- Experimental periodontitis in mice...J Periodontal Res. 2008 Oct 7.
- Leptin induces migration and invasion...Glia. 2008 Sep 23.
- No Association of MMP-7,...Cancer Epidemiol Biomarkers Prev. 2008 Sep;17(9):2514-8.
- Proteomic Analysis in Lung...Chest. 2008 Aug 27.
- MMP-13 is over-expressed in renal...Clin Exp Metastasis. 2008 Aug 16.
- Matrix metalloproteinase 13 is induced...PLoS ONE. 2008 Aug 13;3(8):e2959.
- Oct-3/4 expression reflects tumor...Cancer Res. 2008 Aug 1;68(15):6281-91.
- New pathway links from...J Cell Physiol. 2008 Jul 23.
- In vivo interstitial migration...J Immunol. 2008 Aug 1;181(3):2155-64.
- Steroid receptor coactivator-3/AIB1 promotes...Cancer Res. 2008 Jul 1;68(13):5460-8.
- Is collagenase-3 (MMP-13) expression...Diagn Pathol. 2008 Jun 13;3(1):26.
- Selective modulation of matrix...J Biol Chem. 2008 May 22;.
- CXCL12/CXCR4 promotes laryngeal and hypopharyngeal...Carcinogenesis. 2008 May 16;.
- Tumor-derived Matrix Metalloproteinase-13 (MMP-13)...BMC Cancer. 2008 Mar 28;8(1):83.
- Matrix metalloproteinase (MMP)-1, -9 and -13 as prognostic...Acta Otolaryngol. 2008 Apr;128(4):482-90.
- Expression pattern and circulating...Int J Cancer. 2008 Jun 15;122(12):2805-10.
- Transformation-specific matrix metalloproteinases (MMP)-7...Br J Dermatol. 2008 Apr;158(4):778-85. Epub 2008 Feb 16.
- Characterization of progressive periodontal...J Clin Periodontol. 2008 Mar;35(3):206-14.
Structural Features
MHPGVLAAFLFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENAASSMTERLREMQSFFGLEVT
GKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGI
ADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALM
FPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAEL
FLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGN
QVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC
Cross annotation in other databases
MMP13 in:
Gene Cards
- Diseases
- Expression
- SNP
- Drugs
Other Links
- Human Protein Atlas
- iHOP
- GNF Sym Atlas
- NCBI Homologs
- OMIM
- MEROPS
Functional Attributes in Pathways
-
Substrates : 144 entries in CutDB for M10.013
Ext
- aggrecan 1 isoform 1 precursor
- aggrecan 1 isoform 2 precursor
- Aggrecan 1 isoform 2 precursor
- alpha 1 type I collagen preproprotein
- alpha 1 type II collagen isoform 1
- alpha 1 type II collagen isoform 2, preproprotein
- alpha 1 type XVIII collagen isoform 1 precursor
- alpha 2 type I collagen
- alpha 2 type IV collagen preproprotein
- biglycan preproprotein
- Brevican core protein precursor
- chemokine (C-C motif) ligand 7 precursor
- chemokine (C-X-C motif) ligand 5
- Coagulation factor XII precursor
- coagulation factor XII precursor
- COL9A1 collagen, type IX, alpha 1
- collagen alpha 1(I) (Homo sapiens)
- collagen type III alpha 1 preproprotein
- collagen, type II, alpha 1 isoform 1 precursor
- collagen, type II, alpha 1 isoform 2 precursor
- connective tissue growth factor
- decorin isoform a preproprotein
- decorin isoform b precursor
- decorin isoform c precursor
- fibrillin 1
- fibrinogen, alpha chain isoform alpha preproprotein
- fibrinogen, beta chain preproprotein
- fibrinogen, gamma chain isoform gamma-A precursor
- fibrinogen, gamma chain isoform gamma-B precursor
- Fibromodulin
- fibromodulin precursor
- fibronectin 1
- growth differentiation factor 5 preproprotein
- heparan sulfate proteoglycan core protein
- interleukin 8 precursor
- laminin, gamma 2
- lumican precursor
- matrix metallopeptidase-13 preproprotein
- matrix metalloproteinase 13 preproprotein
- matrix metalloproteinase 9 preproprotein
- matrix metalloproteinase-13
- Monocyte chemoattractant protein (mcp-3)
- opticin precursor
- procollagen, type I, alpha 1
- procollagen, type III, alpha 1
- progelatinase B (Homo sapiens)
- prolactin
- proline arginine-rich end leucine-rich repeat protein precursor
- secreted protein, acidic, cysteine-rich (osteonectin)
- serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
- serpin peptidase inhibitor, clade A, member 3 precursor
- tenascin C (hexabrachion)
- transforming growth factor, beta 3
- Substrate Specificity -- Under development
- Inhibitors -- Under development
- Pathways -- Under development
Recent News and Literature
- Bone morphogenetic protein-2 enhances...Bone. 2008 Nov 6.
- [Relationship between the expression...Zhonghua Bing Li Xue Za Zhi. 2008 Jul;37(7):471-6.
- Experimental periodontitis in mice...J Periodontal Res. 2008 Oct 7.
- Leptin induces migration and invasion...Glia. 2008 Sep 23.
- No Association of MMP-7,...Cancer Epidemiol Biomarkers Prev. 2008 Sep;17(9):2514-8.
- Proteomic Analysis in Lung...Chest. 2008 Aug 27.
- MMP-13 is over-expressed in renal...Clin Exp Metastasis. 2008 Aug 16.
- Matrix metalloproteinase 13 is induced...PLoS ONE. 2008 Aug 13;3(8):e2959.
- Oct-3/4 expression reflects tumor...Cancer Res. 2008 Aug 1;68(15):6281-91.
- New pathway links from...J Cell Physiol. 2008 Jul 23.
- In vivo interstitial migration...J Immunol. 2008 Aug 1;181(3):2155-64.
- Steroid receptor coactivator-3/AIB1 promotes...Cancer Res. 2008 Jul 1;68(13):5460-8.
- Is collagenase-3 (MMP-13) expression...Diagn Pathol. 2008 Jun 13;3(1):26.
- Selective modulation of matrix...J Biol Chem. 2008 May 22;.
- CXCL12/CXCR4 promotes laryngeal and hypopharyngeal...Carcinogenesis. 2008 May 16;.
- Tumor-derived Matrix Metalloproteinase-13 (MMP-13)...BMC Cancer. 2008 Mar 28;8(1):83.
- Matrix metalloproteinase (MMP)-1, -9 and -13 as prognostic...Acta Otolaryngol. 2008 Apr;128(4):482-90.
- Expression pattern and circulating...Int J Cancer. 2008 Jun 15;122(12):2805-10.
- Transformation-specific matrix metalloproteinases (MMP)-7...Br J Dermatol. 2008 Apr;158(4):778-85. Epub 2008 Feb 16.
- Characterization of progressive periodontal...J Clin Periodontol. 2008 Mar;35(3):206-14.
Structural Features
MHPGVLAAFLFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENAASSMTERLREMQSFFGLEVT
GKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGI
ADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALM
FPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAEL
FLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGN
QVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC
Cross annotation in other databases
MMP13 in:
- Gene Cards
- Diseases
- Expression
- SNP
- Drugs
- Other Links
- Human Protein Atlas
- iHOP
- GNF Sym Atlas
- NCBI Homologs
- OMIM
- MEROPS
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