PMAP Toolkit

Tool Name Description
Active Site Recognition Search for active sites of different classes of proteases within the 3D structure.
Predict Disorder in Proteins Use five different algorithms to create consensus prediction of intrinsically disordered regions in proteins (based on FASTA file(s)).
Substrate and Cleavage Site Prediction Build protease specificity models (Position Weight Matrix) from phage display or peptide libraries and predict cut sites in individual proteins, or even the entire proteome.
Proteolytic Dissociation Determine the likelihood that a protein will dissociate into two polypeptides following proteolytic cleavage at a specific site within the 3D structure.